- GRAS exemption claim for isomalto-oligosaccharide or IMO US Food and Drug Administration
Isomalto-Oligosaccharides (IMO)
What are isomalto-oligosaccharides?
Isomalto-oligosaccharides (IMO) are non-digestible short-chain carbohydrates, composed of up to 10 glucose molecules joined by alpha (1,6) bonds [1].
IMO is a mixture of isomaltose, panose, isomaltotriose, isomaltopentose and higher branched oliogsaccharides [1].
Nutrition Facts
- Calories per gram = probably less than 2
- Sweetness, relative to sucrose = 60-70% [1]
Production
IMO is produced from starch obtained from wheat, barley or potatoes, using enzymes [1].
Usage
IMO is used as a sweetener in biscuits, cakes, crackers, nutritional food bars, edible ices, tofu, powdered milk, flavoured drinks, sweet sauces, toppings and syrups, ready-to-eat savouries and snacks.
IMO can be used as an added dietary fiber in certain commercial foods.
IMO is also used as a prebiotic supplement [1].
Safety
IMO in doses up to 30 g/day is Generally Recognized As Safe (GRAS) by the U.S. Food and Drug Administration (FDA) [1].
Dental Caries
IMO is not fermentable by normal mouth bacteria, so it does not promote tooth decay [1].
Gastrointestinal Symptoms
IMO is less fermentable by normal intestinal bacteria than fructooligosaccharides (FOS). IMO in doses 15-20 grams per day should not cause abdominal bloating, nausea, excessive gas or diarrhea [1].
Carbohydrates
- Fructose
- Galactose
- Glucose
- Isomaltose
- Isomaltulose
- Lactose
- Maltose
- Mannose
- Sucrose
- Tagatose
- Trehalose
- Trehalulose
- Xylose
- Erythritol
- Glycerol
- Hydrogenated starch hydrolysates (HSH)
- Inositol
- Isomalt
- Lactitol
- Maltitol
- Mannitol
- Sorbitol
- Xylitol
- Fructo-oligosaccharides (FOS)
- Galacto-oligosaccharides (GOS)
- Human milk oligosaccharides (HMO)
- Isomalto-oligosaccharides (IMO)
- Maltotriose
- Mannan oligosaccharides (MOS)
- Raffinose, stachyose, verbascose
- SOLUBLE FIBER:
- Acacia (arabic) gum
- Agar-agar
- Algin-alginate
- Arabynoxylan
- Beta-glucan
- Beta mannan
- Carageenan gum
- Carob or locust bean gum
- Fenugreek gum
- Galactomannans
- Gellan gum
- Glucomannan or konjac gum
- Guar gum
- Hemicellulose
- Inulin
- Karaya gum
- Pectin
- Polydextrose
- Psyllium husk mucilage
- Resistant starches
- Tara gum
- Tragacanth gum
- Xanthan gum
- INSOLUBLE FIBER:
- Cellulose
- Chitin and chitosan
- FATTY ACIDS
- Saturated
- Monounsaturated
- Polyunsaturated
- Short-chain fatty acids (SCFAs)
- Medium-chain fatty acids (MCFAs)
- Long-chain fatty acids (LCFAs)
- Very long-chain fatty acids (VLCFAs)
- Monoglycerides
- Diglycerides
- Triglycerides
- Vitamin A - Retinol and retinal
- Vitamin B1 - Thiamine
- Vitamin B2 - Riboflavin
- Vitamin B3 - Niacin
- Vitamin B5 - Pantothenic acid
- Vitamin B6 - Pyridoxine
- Vitamin B7 - Biotin
- Vitamin B9 - Folic acid
- Vitamin B12 - Cobalamin
- Choline
- Vitamin C - Ascorbic acid
- Vitamin D - Ergocalciferol and cholecalciferol
- Vitamin E - Tocopherol
- Vitamin K - Phylloquinone
- Curcumin
- FLAVONOIDS:
- Anthocyanidins
- Flavanols: Proanthocyanidins
- Flavanones: Hesperidin
- Flavonols: Quercetin
- Flavones: Diosmin, Luteolin
- Isoflavones: daidzein, genistein
- Caffeic acid
- Chlorogenic acid
- Lignans
- Resveratrol
- Tannins
- Tannic acid
- Alcohol chemical and physical properties
- Alcoholic beverages types (beer, wine, spirits)
- Denatured alcohol
- Alcohol absorption, metabolism, elimination
- Alcohol and body temperature
- Alcohol and the skin
- Alcohol, appetite and digestion
- Neurological effects of alcohol
- Alcohol, hormones and neurotransmitters
- Alcohol and pain
- Alcohol, blood pressure, heart disease and stroke
- Women, pregnancy, children and alcohol
- Alcohol tolerance
- Alcohol, blood glucose and diabetes
- Alcohol intolerance, allergy and headache
- Alcohol and psychological disorders
- Alcohol and vitamin, mineral and protein deficiency
- Alcohol-drug interactions