- Curcumin Linus Pauling Institute
- Curcumin Food and Agriculture Organization
- Turmeric uses, side effects WebMD
- Garg SK et al, 2012, Curcumin for maintenance of remission in ulcerative colitis Cochrane
- Henrotin Y et al, 2013, Curcumin: a new paradigm and therapeutic opportunity for the treatment of osteoarthritis: curcumin for osteoarthritis management PubMed Central
- Chainani-Wu N, 2003, Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa) PubMed
- Dong-wei Z et al, 2013, Curcumin and Diabetes: A Systematic Review PubMed Central
- Sahebkar A et al, 2014, A systematic review and meta-analysis of randomized controlled trials investigating the effects of curcumin on blood lipid PubMed Health
Curcumin
What is curcumin?
Curcumin is a polyphenol (aromatic alcohol), found in turmeric – a spice derived from the roots of a Curcuma longa plant used in South Asia and Middle East [1]. Curcumin is poorly absorbed [2].
Foods High in Curcumin
Foods high in curcumin are turmeric and mustard.
Curcumin as a Food Additive
Curcumin may be used as a yellow-orange color in margarines, butter, cheese, ice creams, yogurts, beverages, popcorn, sweets and other commercial foods. In the European Union, curcumin is labeled as the E-number E100.
Curcumin Supplements
Nonprescription (over-the-counter) curcumin is available as:
- Turmeric supplements (the amount of curcumin in hem may vary a lot)
- Curcumin supplements
Turmeric Health Benefits
There is INSUFFICIENT EVIDENCE [1,2] about the effectiveness of turmeric supplements in the prevention or treatment of Alzheimer’s disease, bruising, cancer (colorectal), cystic fibrosis, diabetes mellitus type 2 [7], diarrhea, fibromyalgia, gum disease (gingivitis), headache, high cholesterol [8], inflammatory diseases [6] (anterior uveitis, Crohn’s disease, hepatitis, lupus nephritis, osteoarthritis [5], ulcerative colitis [4]), irritable bowel syndrome (IBS), itchy skin, lichen planus, liver and gallbladder problems, menstrual problems, pain, recovery from surgery, rheumatoid arthritis, ringworm, stomach ulcers caused by Helicobacter pylori (H pylori) infection, stomach upset (dyspepsia), tuberculosis or in stimulating immunity or as an antioxidant [1].
Curcumin Safety: Side Effects, Toxicity
Turmeric supplements are LIKELY SAFE when taken by mouth or applied on the skin [2].
Side effects may include stomach upset, nausea, dizziness or diarrhea.
During Pregnancy
Turmeric supplements are LIKELY UNSAFE during pregnancy.
No serious side effects or toxicity of curcumin have been observed so far, but pregnant and breastfeeding women should avoid it since its effect on unborn babies were not sufficiently tested so far [1]. Women undergoing chemotherapy for breast cancer should also avoid curcumin supplements [1].
Turmeric-Drug Interactions
Turmeric supplements may slow blood clotting and can therefore increase the risk of bleeding when taken together with anti-clotting drugs, such as aspirin, clopidogrel, diclofenac, ibuprofen, naproxen, dalteparin, enoxaparin, heparin or warfarin [2].
Phytonutrients
- Curcumin
- FLAVONOIDS:
- Anthocyanidins
- Flavanols: Proanthocyanidins
- Flavanones: Hesperidin
- Flavonols: Quercetin
- Flavones: Diosmin, Luteolin
- Isoflavones: daidzein, genistein
- Caffeic acid
- Chlorogenic acid
- Lignans
- Resveratrol
- Tannins
- Tannic acid
- Fructose
- Galactose
- Glucose
- Isomaltose
- Isomaltulose
- Lactose
- Maltose
- Mannose
- Sucrose
- Tagatose
- Trehalose
- Trehalulose
- Xylose
- Erythritol
- Glycerol
- Hydrogenated starch hydrolysates (HSH)
- Inositol
- Isomalt
- Lactitol
- Maltitol
- Mannitol
- Sorbitol
- Xylitol
- Fructo-oligosaccharides (FOS)
- Galacto-oligosaccharides (GOS)
- Human milk oligosaccharides (HMO)
- Isomalto-oligosaccharides (IMO)
- Maltotriose
- Mannan oligosaccharides (MOS)
- Raffinose, stachyose, verbascose
- SOLUBLE FIBER:
- Acacia (arabic) gum
- Agar-agar
- Algin-alginate
- Arabynoxylan
- Beta-glucan
- Beta mannan
- Carageenan gum
- Carob or locust bean gum
- Fenugreek gum
- Galactomannans
- Gellan gum
- Glucomannan or konjac gum
- Guar gum
- Hemicellulose
- Inulin
- Karaya gum
- Pectin
- Polydextrose
- Psyllium husk mucilage
- Resistant starches
- Tara gum
- Tragacanth gum
- Xanthan gum
- INSOLUBLE FIBER:
- Cellulose
- Chitin and chitosan
- FATTY ACIDS
- Saturated
- Monounsaturated
- Polyunsaturated
- Short-chain fatty acids (SCFAs)
- Medium-chain fatty acids (MCFAs)
- Long-chain fatty acids (LCFAs)
- Very long-chain fatty acids (VLCFAs)
- Monoglycerides
- Diglycerides
- Triglycerides
- Vitamin A - Retinol and retinal
- Vitamin B1 - Thiamine
- Vitamin B2 - Riboflavin
- Vitamin B3 - Niacin
- Vitamin B5 - Pantothenic acid
- Vitamin B6 - Pyridoxine
- Vitamin B7 - Biotin
- Vitamin B9 - Folic acid
- Vitamin B12 - Cobalamin
- Choline
- Vitamin C - Ascorbic acid
- Vitamin D - Ergocalciferol and cholecalciferol
- Vitamin E - Tocopherol
- Vitamin K - Phylloquinone
- Alcohol chemical and physical properties
- Alcoholic beverages types (beer, wine, spirits)
- Denatured alcohol
- Alcohol absorption, metabolism, elimination
- Alcohol and body temperature
- Alcohol and the skin
- Alcohol, appetite and digestion
- Neurological effects of alcohol
- Alcohol, hormones and neurotransmitters
- Alcohol and pain
- Alcohol, blood pressure, heart disease and stroke
- Women, pregnancy, children and alcohol
- Alcohol tolerance
- Alcohol, blood glucose and diabetes
- Alcohol intolerance, allergy and headache
- Alcohol and psychological disorders
- Alcohol and vitamin, mineral and protein deficiency
- Alcohol-drug interactions