- Chlorophyll and chlorophyllin Linus Pauling Institute
- Chlorophyllin uses, side effects WebMD
- Egner PA et al, 2001, Chlorophyllin intervention reduces aflatoxin–DNA adducts in individuals at high risk for liver cancer PubMed Central
- Nahata MC et al, 1983, Effect of chlorophyllin on urinary odor in incontinent geriatric patients PubMed
Chlorophyll and Chlorophyllin
What is chlorophyll?
Chlorophyll is a pigment that gives the plant leaves their green color; it absorbs ultraviolet light and thus provides energy for photosynthesis. Chlorophyllin is a semi-synthetic mixture of sodium-copper salts derived from chlorophyll and used as supplements [1].
Foods High in Chlorophyll
- PLANT FOODS: green leafy vegetables (spinach, garden cress, green beans, arugula, leeks, endive, Chinese cabbage), green beans, sugar peas, spirulina [1].
Chlorophyllin as a Food Additive
Sodium copper chlorophyllin may be used as a green color in beverages, jams, jellies, candies, cakes, ice creams, other commercial foods, and certain drugs [1]. In the European Union, chlorophyll and chlorophyllins are labeled as the E-number E141.
Chlorophyll and Chlorophyllin Supplements
Nonprescription (over-the-counter) oral supplements [1]:
- Chlorophyl supplements in the form of green algae, such as chlorella
- Sodium-copper chlorophyllin (chlorophyllin-copper complex)
Chlorophyll and Chlorophyllin Health Benefits
Chlorophyllin supplements are POSSIBLY INEFFECTIVE to reduce urine odor in individuals with urine incontinence [2,4].
There is INSUFFICIENT EVIDENCE [1,2] about the effectiveness of chlorophyll or chlorophyllin supplements in the prevention or treatment of cancer (colorectal, liver), constipation or excessive gas (flatulence), in promoting wound healing (when used topically) or in reducing body or stool odor in people with colonostomias or ileostomias.
In one study in Chinese population, chlorophyllin supplements before meals significantly decrease the absorption of aflatoxin–a known liver carcinogen; this may, in theory, reduce the risk of liver cancer in people who consume a lot of foods high in aflatoxin, such as corn, peanuts, soy sauce, and fermented soy beans [3].
Chlorophyllin Safety: Side Effects, Toxicity
No serious side effects or toxicities of chlorophyll or chlorophyllin have been observed, so far. Diarrhea may occasionally occur. Chlorophyllin supplements may color the tongue yellow or black, and color the urine or stool green.
Not enough is known about the safety of chlorophyll and chlorophyllin supplements during pregnancy and breastfeeding, so women in these periods should avoid them [2].
Oral chlorophyllin may result in false positive guaiac stool test for occult blood [1].
Phytonutrients
- Curcumin
- FLAVONOIDS:
- Anthocyanidins
- Flavanols: Proanthocyanidins
- Flavanones: Hesperidin
- Flavonols: Quercetin
- Flavones: Diosmin, Luteolin
- Isoflavones: daidzein, genistein
- Caffeic acid
- Chlorogenic acid
- Lignans
- Resveratrol
- Tannins
- Tannic acid
- Fructose
- Galactose
- Glucose
- Isomaltose
- Isomaltulose
- Lactose
- Maltose
- Mannose
- Sucrose
- Tagatose
- Trehalose
- Trehalulose
- Xylose
- Erythritol
- Glycerol
- Hydrogenated starch hydrolysates (HSH)
- Inositol
- Isomalt
- Lactitol
- Maltitol
- Mannitol
- Sorbitol
- Xylitol
- Fructo-oligosaccharides (FOS)
- Galacto-oligosaccharides (GOS)
- Human milk oligosaccharides (HMO)
- Isomalto-oligosaccharides (IMO)
- Maltotriose
- Mannan oligosaccharides (MOS)
- Raffinose, stachyose, verbascose
- SOLUBLE FIBER:
- Acacia (arabic) gum
- Agar-agar
- Algin-alginate
- Arabynoxylan
- Beta-glucan
- Beta mannan
- Carageenan gum
- Carob or locust bean gum
- Fenugreek gum
- Galactomannans
- Gellan gum
- Glucomannan or konjac gum
- Guar gum
- Hemicellulose
- Inulin
- Karaya gum
- Pectin
- Polydextrose
- Psyllium husk mucilage
- Resistant starches
- Tara gum
- Tragacanth gum
- Xanthan gum
- INSOLUBLE FIBER:
- Cellulose
- Chitin and chitosan
- FATTY ACIDS
- Saturated
- Monounsaturated
- Polyunsaturated
- Short-chain fatty acids (SCFAs)
- Medium-chain fatty acids (MCFAs)
- Long-chain fatty acids (LCFAs)
- Very long-chain fatty acids (VLCFAs)
- Monoglycerides
- Diglycerides
- Triglycerides
- Vitamin A - Retinol and retinal
- Vitamin B1 - Thiamine
- Vitamin B2 - Riboflavin
- Vitamin B3 - Niacin
- Vitamin B5 - Pantothenic acid
- Vitamin B6 - Pyridoxine
- Vitamin B7 - Biotin
- Vitamin B9 - Folic acid
- Vitamin B12 - Cobalamin
- Choline
- Vitamin C - Ascorbic acid
- Vitamin D - Ergocalciferol and cholecalciferol
- Vitamin E - Tocopherol
- Vitamin K - Phylloquinone
- Alcohol chemical and physical properties
- Alcoholic beverages types (beer, wine, spirits)
- Denatured alcohol
- Alcohol absorption, metabolism, elimination
- Alcohol and body temperature
- Alcohol and the skin
- Alcohol, appetite and digestion
- Neurological effects of alcohol
- Alcohol, hormones and neurotransmitters
- Alcohol and pain
- Alcohol, blood pressure, heart disease and stroke
- Women, pregnancy, children and alcohol
- Alcohol tolerance
- Alcohol, blood glucose and diabetes
- Alcohol intolerance, allergy and headache
- Alcohol and psychological disorders
- Alcohol and vitamin, mineral and protein deficiency
- Alcohol-drug interactions
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