- Malainer C, 2010, master thesis: Enzymatic synthesis and investigation of novel galacto-oligosaccharides Universitat fur Bodenkultur
- Engfer MB et al, 2000, Human milk oligosaccharides are resistant to enzymatic hydrolysis in the upper gastrointestinal tract The American Journal of Nutrition
- Roberfroid, M., 2007, Prebiotics: the concept revisited The Journal of Nutrition
- Bode L, 2012, Human milk oligosaccharides: Every baby needs a sugar mama PubMed Central
- McGuire W, 2003, Donor human milk versus formula for preventing necrotising enterocolitis in preterm infants: systematic review BMJ
Home / Carbohydrates / Human Milk Oligosaccharides (HMO)
Human Milk Oligosaccharides (HMO)
What are human milk oligosaccharides (HMO)?
Human milk oligosaccharides (HMO) are a mixture of indigestible oligosaccharides composed of glucose, galactose, fucose, sialic acid and N-acetyl-glucosamine [1]. Human breast milk contains about 5-10 grams HOS per liter (cow’s milk in infant formula contains only traces of oligosaccharides) [1]. HMO is considered a soluble fiber [2].
Possible HMO Benefits
SUGGESTED HMO EFFECTS, but more studies warranted [2]:
- HMO may reduce the attachment of bacteria in the throat, esophagus and small intestine and thus help to prevent respiratory and gastrointestinal infections [2].
- HMO is absorbed partly intact and excreted in the urine, and may be protective against urinary tract infections [1].
- HMO may help to prevent necrotizing enterocolitis (NEC)–a severe inflammation of the intestine–in sick infants, especially premature infants [5].
HMO is PROBABLY NOT EFFECTIVE as a prebiotic (a substance that promotes the growth of beneficial intestinal bacteria) [3,4].
Related Nutrients
Carbohydrates
- Fructose
- Galactose
- Glucose
- Isomaltose
- Isomaltulose
- Lactose
- Maltose
- Mannose
- Sucrose
- Tagatose
- Trehalose
- Trehalulose
- Xylose
- Erythritol
- Glycerol
- Hydrogenated starch hydrolysates (HSH)
- Inositol
- Isomalt
- Lactitol
- Maltitol
- Mannitol
- Sorbitol
- Xylitol
- Fructo-oligosaccharides (FOS)
- Galacto-oligosaccharides (GOS)
- Human milk oligosaccharides (HMO)
- Isomalto-oligosaccharides (IMO)
- Maltotriose
- Mannan oligosaccharides (MOS)
- Raffinose, stachyose, verbascose
- SOLUBLE FIBER:
- Acacia (arabic) gum
- Agar-agar
- Algin-alginate
- Arabynoxylan
- Beta-glucan
- Beta mannan
- Carageenan gum
- Carob or locust bean gum
- Fenugreek gum
- Galactomannans
- Gellan gum
- Glucomannan or konjac gum
- Guar gum
- Hemicellulose
- Inulin
- Karaya gum
- Pectin
- Polydextrose
- Psyllium husk mucilage
- Resistant starches
- Tara gum
- Tragacanth gum
- Xanthan gum
- INSOLUBLE FIBER:
- Cellulose
- Chitin and chitosan
- FATTY ACIDS
- Saturated
- Monounsaturated
- Polyunsaturated
- Short-chain fatty acids (SCFAs)
- Medium-chain fatty acids (MCFAs)
- Long-chain fatty acids (LCFAs)
- Very long-chain fatty acids (VLCFAs)
- Monoglycerides
- Diglycerides
- Triglycerides
- Vitamin A - Retinol and retinal
- Vitamin B1 - Thiamine
- Vitamin B2 - Riboflavin
- Vitamin B3 - Niacin
- Vitamin B5 - Pantothenic acid
- Vitamin B6 - Pyridoxine
- Vitamin B7 - Biotin
- Vitamin B9 - Folic acid
- Vitamin B12 - Cobalamin
- Choline
- Vitamin C - Ascorbic acid
- Vitamin D - Ergocalciferol and cholecalciferol
- Vitamin E - Tocopherol
- Vitamin K - Phylloquinone
- Curcumin
- FLAVONOIDS:
- Anthocyanidins
- Flavanols: Proanthocyanidins
- Flavanones: Hesperidin
- Flavonols: Quercetin
- Flavones: Diosmin, Luteolin
- Isoflavones: daidzein, genistein
- Caffeic acid
- Chlorogenic acid
- Lignans
- Resveratrol
- Tannins
- Tannic acid
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